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The Pardee Lab

At the interface of synthetic biology and human health

About Us

The Pardee Lab is part of the Graduate Department of Pharmaceutical Sciences at the University of Toronto .  The lab seeks to impact human health by developing portable, affordable tools using the principles of synthetic biology.  We have recently developed two exciting new biotechnologies that aim to enable low cost and distributed healthcare.  The first is a portable platform for low cost molecular diagnostics and the second is a system for the portable manufacture of therapeutics outside of the laboratory.  Both systems are based on freeze-dried, cell-free biochemical reactions that are activated by simply adding water. 
 
We see cell-free technologies as important tools in meeting challenges that face health care systems at home and abroad.  As we have demonstrated, cell-free hosting of diagnostics and drug manufacturing offers a paradigm shift in how health care systems can adapt rapidly to public health needs, provide emergency response and extend lab-grade molecular capabilities into virtually any environment.  Such applications are enabled by freeze-dried cell-free (FD-CF) enzymes that are sterile yet retain the properties of cellular transcription and translation for deploying poised molecular components to the field. 
Learn MORE

Pardee Lab Online and in the News

  • August 9, 2018 U of T News
  • ​​July 25, 2018 Canadian Geographic 
  • ​July 16, 2017 Medicine by Design
  • June 25, 2017 Wall Street Journal 
  • May 13, 2017 PLoS Blog  
  • March 16, 2017  CIHR/IDRC Zika virus Team grant 
  • Oct 12, 2016 The Atlantic 
  • Oct 16, 2016 Popular Science Best of What’s New  
  • September 23, 2016 Science Daily
  • Aug 30, 2016 Addgene blog post
  • June 22, 2016 Disruptive Podcast
  • May 30, 2016. Trends in Molecular Medicine
  • May 20, 2016 BioTechniques
  • May 6, 2016 New York Times
  • May 6, 2016 ResearchGate Interview
  • May 6, 2016 Globe and Mail 
  • May 6, 2016 Harvard Gazette
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  • Home
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