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Keith Pardee
Associate professor, Leslie Dan Faculty of Pharmacy 
University of Toronto
Canada Research Chair in Synthetic Biology and Human Health
Co-Director, PRiME, Precision Medicine Initiative
Medicine by Design Investigator



 




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Our lab works in the field of synthetic biology, specifically we are pioneering in vitro devices to host cell-free synthetic gene networks for broad applications in human health. Through these efforts we are using the cell-free platform to lower the cost and technical barriers to accessing health care.  To do this we freeze-dry the enzymes of transcription and translation, along with genetically encoded tools, into porous materials such as paper.  We have used this approach to create a sterile and abiotic platform for low-cost diagnostics for Ebola, Zika, chikungunya, SARS-CoV-2 viruses, amongst other pathogens, and have also created a platform for making vaccines in the field.  Through ongoing projects, we are pushing the field in exciting directions, integrating molecular engineering with hardware, and applying cell-free expression broadly to applications in biomedical research.  

EDUCATION AND TRAINING
PDF       Wyss Institute, Harvard University
              Synthetic Biology, Jim Collins
PhD      Molecular Genetics, University of Toronto
              Protein structure/function, Aled Edwards/Henry Krause
MSc      Botany, University of British Columbia
              Natural Products Chemistry, Neil GHN Towers, Chris French
BSc       Biological Science, University of Alberta
              Botany
 
PROFESSIONAL ACTIVITIES
Broad member, Canadian Council of Engineering Biology  2022-present
Co-Director, PRiME: A Precision Medicine Initiative, University of Toronto  2021-present
Co-Founder and Advisor, En Carta Diagnostics  2021-present
Member, Medicine by Design 2.0 Strategic Planning Committee  2021-present
Co-Founder and Board Director, LSK Technologies  2020-present
Co-Founder and Advisor, Liberum Biotech  2020-present
Member, National Committee of Can-DESyNe  2019-2022
Science mentor, Creative Destruction Lab  2016-present
 
AWARDS AND HONOURS
2016-2026  Canada Research Chair. CIHR. Synthetic Biology and Human Health (Tier II) 
2021-2026  Early Researcher Award, Ontario Ministry of Colleges and Universities  
2016-2023  Medicine by Design Investigator, University of Toronto
2021  Early Career Supervision Award , School of Graduate Studies, University of Toronto
2016-2021  Canada Research Chair. CIHR. Synthetic Biology and Human Health (Tier II)
2019  US Office of Naval Research Visiting Scientist Program 
2018  Emerging Leaders in Biosecurity Fellow, Johns Hopkins University 
2017  New Investigator Research Award, Association of Faculties of Pharmacy of Canada                 
​2017  Nominee and Honoree of Webby Award (Zika diagnostics podcast, Disruptive) 
2017  Katerva Award Nominee and Finalist                                                    
2016-present  Medicine by Design Investigator, University of Toronto 
2016  Popular Science Best of What’s New Award - Health                      
2011-2014  CIHR Postdoctoral Fellowship                                                      
2010  Donnelly Centre Dissertation Prize, University of Toronto            
2006  National Institutes of Health Travel Award                                         
2004  Ontario Graduate Scholarship                                                                 
2002  NSERC Postgraduate Scholarship
2000 Graduate Engineering and Technology Scholarship, Science Council British Columbia 
​2000  University Graduate Fellowship, University of British Columbia

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  • Home
  • Keith Pardee
  • Research
  • Publications
  • TEAM
  • Alumni
  • GALLERY
  • OPEN POSITIONS
  • Contact